Embedding of Precision-Cut Lung Slices in Engineered Hydrogel Biomaterials Supports Extended Ex Vivo Culture

Precision-cut lung slices are very thin slices of lung tissue that can be kept alive in culture outside of the body and studied as a model for a variety of chronic pulmonary diseases. Unfortunately, slices alone are only viable for about a week, which is not enough time to study disease mechanisms and treatment. The … Continue reading Embedding of Precision-Cut Lung Slices in Engineered Hydrogel Biomaterials Supports Extended Ex Vivo Culture

Peptide-functionalized hydrogels modulate integrin expression and stemness in adult human epidermal keratinocytes

Duncan Davis-Hall, MS; Vy Nguyen, BS; Tyler D’Ovidio, BS; Ethan Tsai, PhD; Ganna Bilousova, PhD; and Chelsea M. Magin, PhD https://doi.org/10.1002/adbi.201900022             Check out the Magin Lab’s first primary research article, published recently in Advanced Biosystems and featured on the journal’s cover! This is the culmination of Duncan Davis-Hall’s work as a Master’s student in … Continue reading Peptide-functionalized hydrogels modulate integrin expression and stemness in adult human epidermal keratinocytes

Graduating Pulmonary Science and Critical Care MD Fellow: A reflection on two years of science!

By. Kolene E. Bailey, MD My name is Kolene E. Bailey, and for the last 2 years, I have been an MD research fellow in Dr. Chelsea Magin's Lab. My love of science and engineering began back in my undergraduate training as a major in biological engineering and minor in biomedical engineering while at Cornell University … Continue reading Graduating Pulmonary Science and Critical Care MD Fellow: A reflection on two years of science!

Outstanding Graduate Student Award 2019

By: Duncan Davis-Hall I was honored with the CU Bioengineering Department’s Outstanding Graduate Student Award at the BIOE graduation banquet on May 15, 2019. This award is given to one current BIOE graduate student every year and recognizes dedication to scientific pursuit, extracurricular activities, and outreach. Dr. Chelsea Magin nominated me for the Outstanding Graduate … Continue reading Outstanding Graduate Student Award 2019

American Thoracic Society (ATS) International Conference

By: Kolene E. Bailey, MD The American Thoracic Society (ATS) International Conference is the home of pulmonary, critical care, and sleep professionals, from those in the earliest stages of their careers to those whose research or strides in clinical care has gained them international recognition. This year we took a trip to Dallas, TX to … Continue reading American Thoracic Society (ATS) International Conference

Publication: Tissue-Informed Engineering Strategies for Modeling Human Pulmonary Diseases

Our review in APJ-Lung highlights how advances in lung tissue characterization reveal dynamic changes in the structure, mechanics and composition of the extracellular matrix in chronic pulmonary diseases, and how this information paves the way for tissue-informed engineering of more organotypic models of human pathology. We envision that engineering strategies using precision biomaterials and advanced … Continue reading Publication: Tissue-Informed Engineering Strategies for Modeling Human Pulmonary Diseases