Embedding of Precision-Cut Lung Slices in Engineered Hydrogel Biomaterials Supports Extended Ex Vivo Culture

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Precision-cut lung slices are very thin slices of lung tissue that can be kept alive in culture outside of the body and studied as a model for a variety of chronic pulmonary diseases. Unfortunately, slices alone are only viable for about a week, which is not enough time to study disease mechanisms and treatment. The Magin Lab has used a hydrogel embedding process to maintain precision-cut lung slice viability ex vivo for up to 21 days. Check out our paper on the research published in the January 2020 issue of the American Journal of Respiratory Cell and Molecular Biology here!

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